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Models

Nerves

  • Hindlimb: sciatic
  • Forelimb: median, ulnar

Injuries

  • Crush (axonotmesis)
  • Complete transection followed by microsurgical nerve reconstruction (neurotmesis)

Test-compound administration

Routes

  • Epidural
  • Intrathecal
  • Intracerebroventricular
  • Others: i.v., s.c., p.o., i.p., i.m…

Dose regimen

  • Single, repeated or chronic (osmotic pump)

Functional recovery study

  • Walking track analysis
  • Grasping test

Validation data

Click below to see a sample data set